Role and contribution
Andrea Mattevi is professor of Molecular Biology at the University of Pavia (Italy) where he co-ordinates the protein crystallography group. The common theme to his research projects has been the investigation of medically relevant enzymes with interesting chemical properties, such as complex multifunctional systems and proteins performing unusual catalytic functions. The core of the research activity is represented by X-ray crystallography, employed to study protein three-dimensional structures. This is, however, complemented by other approaches such as site-directed mutagenesis, analysis of enzyme kinetics and computational chemistry. The laboratory has received funding by national and international agencies, including the National Institute of Health (USA), the European Community and pharmaceutical companies. Andrea Mattevi is currently a EMBO Young Investigator. The people involved in the Vizier project are : A. Mattevi, who is the Principal Investigator. He has 58 published articles in refereed journals and has deposited 94 structures in the PDB. C. Binda is a Young Scientist (Unipv) in charge of the crystallisation robots use and maintenance. S. Rovida, Technical Assistant, is in charge of diffraction platform. L. Decolibus, a PhD student, will contribute to the crystallographic analysis of the viral proteins.
UNIPV Pavia, IT
